Article
Systematic gene deletion and functional characterization of histidine kinase phosphorelay receptors (HKRs) in the human pathogenic fungus Aspergillus fumigatus.
Fungal genetics and biology : FG & B - 1 Nov 2015
Chapeland-Leclerc F, Dilmaghani A, Ez-Zaki L, Boisnard S, Da Silva B, Gaslonde T, Porée F H, Ruprich-Robert G
Abstract excerpt
Histidine kinase receptors (HKRs) appear to be a common strategy for model and pathogenic fungi to sense and respond to environmental stresses. In the human pathogen Aspergillus fumigatus, which is responsible for invasive aspergillosis, 13 genes potentially encoding HKRs have been identified. Until now, only three HKRs have been functionally characterized. The aim of this study was to perform the systematic...
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