Article
Differential involvement of histidine kinase receptors in pseudohyphal development, stress adaptation, and drug sensitivity of the opportunistic yeast Candida lusitaniae.
Eukaryotic cell - 1 Oct 2007
Chapeland-Leclerc Florence, Paccallet Paméla, Ruprich-Robert Gwenaël, Reboutier David, Chastin Christiane, Papon Nicolas
Abstract excerpt
Fungal histidine kinase receptors (HKRs) sense and transduce many extracellular signals. We investigated the role of HKRs in morphogenetic transition, osmotolerance, oxidative stress response, and mating ability in the opportunistic yeast Candida lusitaniae. We isolated three genes, SLN1, NIK1, and CHK1, potentially encoding HKRs of classes VI, III, and X, respectively. These genes were disrupted by a...
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