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Article

Dectin-1 Polymorphism: A Genetic Disease Specifier in Autism Spectrum Disorders?

PloS one - 1 Jan 2015

Bennabi Meriem, Delorme Richard, Oliveira José, Fortier Catherine, Lajnef Mohamed, Boukouaci Wahid, Feugeas Jean-Paul, Marzais François, Gaman Alexandru, Charron Dominique, Ghaleh Bijan, Krishnamoorthy Rajagopal, Leboyer Marion, Tamouza Ryad

Abstract excerpt

INTRODUCTION: In autism spectrum disorders (ASD), complex gene-environment interactions contribute to disease onset and progress. Given that gastro-intestinal dysfunctions are common in ASD, we postulated involvement of microbial dysbiosis in ASD and investigated, under a case-control design, the influence of DNA polymorphisms in the CLEC7A gene that encodes a pivotal fungal sensor, Dectin-1. MATERIAL AND...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26352598
DOI: 10.1371/journal.pone.0137339
PMCID: PMC4564239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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