Article
Screening and advanced lipid phenotyping in familial hypercholesterolemia: The Very Large Database of Lipids Study-17 (VLDL-17).
Journal of clinical lipidology - 1 Jan 2000
Miller P Elliott, Martin Seth S, Toth Peter P, Santos Raul D, Blaha Michael J, Nasir Khurram, Virani Salim S, Post Wendy S, Blumenthal Roger S, Jones Steven R
Abstract excerpt
BACKGROUND: Familial hypercholesterolemia (FH) is an autosomal dominant dyslipidemia characterized by defective low-density lipoprotein (LDL) clearance. The aim of this study was to compare Friedewald-estimated LDL cholesterol (LDL-C) to biologic LDL-C in individuals screening positive for FH and then further characterize FH phenotypes. METHODS: We studied 1,320,581 individuals from the Very Large Database of...
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