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Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoir

9 Sept 2015

Abstract excerpt

HIV persists in latently infected cells of patients on antiretroviral therapy (ART). This persistent proviral DNA reservoir is an important predictor of viral rebound upon therapy failure or interruption and forms a major obstacle towards cure. Accurate quantification of the low levels of persisting HIV DNA may aid patient monitoring and cure research. Digital PCR is a promising tool that enables direct absolute...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26350506
DOI: 10.1038/srep13811

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