Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Accuracy of real-time PCR and digital PCR for the monitoring of total HIV DNA under prolonged antiretroviral therapy

4 Jun 2022

Abstract excerpt

Abstract Total HIV DNA is a standard marker to monitor the HIV reservoir in people living with HIV. We investigated HIV DNA quantification accuracy by a real-time PCR kit (qPCR) and digital PCR (dPCR) method within the same set of primers and probes. Among 48 aviremic patients followed for up to 7 years with qPCR, the mean coefficient of variation of total HIV DNA between two successive measurements was 77% (±...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35665775
DOI: 10.1038/s41598-022-13581-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Accuracy of real-time PCR and digital PCR for the monitoring of total HIV DNA under prolonged antiretroviral therapyPMID 35665775Read ↗

Total HIV DNA: a global marker of HIV persistenceSemantic proximity Read ↗

Digital PCR as a tool to measure HIV persistenceSemantic proximity Read ↗

Instability of 8E5 calibration standard revealed by digital PCR risks inaccurate quantification of HIV DNA in clinical samples by qPCRSemantic proximity Read ↗

Quantification of HIV-DNA and residual viremia in patients starting ART by droplet digital PCR: Their dynamic decay and correlations with immunological parameters and virological successSemantic proximity Read ↗

Quantification of Total HIV DNA as a Marker to Measure Viral Reservoir: Methods and Potential Implications for Clinical PracticeSemantic proximity Read ↗

Comparison of digital PCR platforms and semi-nested qPCR as a tool to determine the size of the HIV reservoirSemantic proximity Read ↗

New Tools for Quantifying HIV-1 Reservoirs: Plasma RNA Single Copy Assays and BeyondSemantic proximity Read ↗

A higher CD4/CD8 ratio correlates with an ultralow cell-associated HIV-1 DNA level in chronically infected patients on antiretroviral therapy: a case control studySemantic proximity Read ↗

Diagnostic utility of droplet digital PCR for HIV reservoir quantificationSemantic proximity Read ↗

Integrated and Total HIV-1 DNA Predict Ex Vivo Viral OutgrowthSemantic proximity Read ↗

Quantification of Total and 2-LTR (Long terminal repeat) HIV DNA, HIV RNA and Herpesvirus DNA in PBMCsSemantic proximity Read ↗

Triplex digital PCR assays for the quantification of intact proviral HIV-1 DNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.