Article
Comparison of Iron-Binding Ability Between Thr70-NapA and Ser70-NapA of Helicobacter pylori.
Helicobacter - 1 Jun 2016
Shan Weiran, Kung Hsiang-Fu, Ge Ruiguang
Abstract excerpt
BACKGROUND: The neutrophil-activating protein (NapA) of Helicobacter pylori (H. pylori), with DNA-binding and iron seizing properties, is a fundamental virulence factor involved in H. pylori-related diseases. Compared with Ser70-NapA strain, Thr70-NapA strain is more intimately correlated with iron-deficiency anemia. METHODS: To investigate whether two types of proteins differ in iron-binding ability, mutated...
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