Article
[Aberrant micro RNA and epigenetic network are associated with progression from MGUS to multiple myeloma].
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Aug 2015
Handa Hiroshi
Abstract excerpt
In recent years, attention has been drawn to aberrant epigenetics as well as coding gene mutations in cancers. DNA methylation, histone acetylation and methylation, and micro RNA (miRNA) are included in the field of epigenetics. miRNAs are small RNAs of only 19-25 bases in length which do not encode protein but do they control gene expression by destroying mRNA or inhibiting translation. In multiple myeloma (MM),...
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