The rs1572931 polymorphism of the RAB7L1 gene promoter is associated with reduced risk of Parkinson's disease.

doi:10.1179/1743132815Y.0000000085

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The rs1572931 polymorphism of the RAB7L1 gene promoter is associated with reduced risk of Parkinson's disease.

Neurological research - 1 Nov 2015

Goudarzian Maryam, Khaligh Ali, Fourozan Reza, Jamal Mirmoosavi Seyed, Darvish Hossein, Safaralizadeh Tannaz, Emamalizadeh Babak

Abstract excerpt

INTRODUCTION: Parkinson's disease (PD) is one of the most common neurologic disorders affecting about 2% of people over 65 years old and both genetic and environmental factors are involved in its aetiology. The genetic part includes several genes and polymorphisms that are the direct cause of disease or its susceptibility factor. The rs1572931 polymorphism of RAB7L1 gene, located in the promoter region, has been...

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PMID: 26344175
DOI: 10.1179/1743132815Y.0000000085

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