Article
The Diverse Forms of Lactose Intolerance and the Putative Linkage to Several Cancers.
Nutrients - 28 Aug 2015
Amiri Mahdi, Diekmann Lena, von Köckritz-Blickwede Maren, Naim Hassan Y
Abstract excerpt
Lactase-phlorizin hydrolase (LPH) is a membrane glycoprotein and the only β-galactosidase of the brush border membrane of the intestinal epithelium. Besides active transcription, expression of the active LPH requires different maturation steps of the polypeptide through the secretory pathway, including N- and O-glycosylation, dimerization and proteolytic cleavage steps. The inability to digest lactose due to...
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