Article
Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry.
The Journal of allergy and clinical immunology - 1 Jan 2016
Cetica Valentina, Sieni Elena, Pende Daniela, Danesino Cesare, De Fusco Carmen, Locatelli Franco, Micalizzi Concetta, Putti Maria Caterina, Biondi Andrea, Fagioli Franca, Moretta Lorenzo, Griffiths Gillian M, Luzzatto Lucio, Aricò Maurizio
Abstract excerpt
BACKGROUND: Hemophagocytic lymphohistiocytosis (HLH) is a rare life-threatening disease affecting mostly children but also adults and characterized by hyperinflammatory features. A subset of patients, referred to as having familial hemophagocytic lymphohistiocytosis (FHL), have various underlying genetic abnormalities, the frequencies of which have not been systematically determined previously. OBJECTIVE: This...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.