Article
Neoepitopes of Cancers: Looking Back, Looking Ahead.
Cancer immunology research - 1 Sept 2015
Srivastava Pramod K
Abstract excerpt
The search for specificity in cancers has been a holy grail in cancer immunology. Cancer geneticists have long known that cancers harbor transforming and other mutations. Immunologists have long known that inbred mice can be immunized against syngeneic cancers, indicating the existence of cancer-specific antigens. With the technological advances in high-throughput DNA sequencing and bioinformatics, the genetic...
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