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Article

Tumor neoantigens: building a framework for personalized cancer immunotherapy.

The Journal of clinical investigation - 1 Sept 2015

Gubin Matthew M, Artyomov Maxim N, Mardis Elaine R, Schreiber Robert D

Abstract excerpt

It is now well established that the immune system can recognize developing cancers and that therapeutic manipulation of immunity can induce tumor regression. The capacity to manifest remarkably durable responses in some patients has been ascribed in part to T cells that can (a) kill tumor cells directly, (b) orchestrate diverse antitumor immune responses, (c) manifest long-lasting memory, and (d) display...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26258412
DOI: 10.1172/JCI80008
PMCID: PMC4588307

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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