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Article

Evaluation of CTNNB1 and TP53 variability in patients with hepatocellular carcinoma and occult hepatitis B virus infection.

Cancer genetics - 1 Oct 2015

Saitta Carlo, Lanza Marika, Bertuccio Antonio, Lazzara Salvatore, Navarra Giuseppe, Raimondo Giovanni, Pollicino Teresa

Abstract excerpt

Hepatitis B virus (HBV) infection plays a major role in hepatocellular carcinoma (HCC) development. Much evidence suggests that HBV also maintains its pro-oncogenic properties in cases of occult HBV infection (OBI). Mutations of the beta-catenin and p53 genes (CTNNB1 and TP53, respectively) may be associated with HCC occurrence in patients with overt HBV infection, whereas such genetic mutations have not been...

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Source

Identifiers

PMID: 26341700
DOI: 10.1016/j.cancergen.2015.07.002

Genes

CTNNB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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