Article
Viral sequence analysis of occult HBV infection and its reactivation in immunosuppressed patients.
Journal of biological regulators and homeostatic agents - 1 Jan 2000
Ferraro D, Pizzillo P, Urone N, Iannitto E, Craxi A, Di Stefano R
Abstract excerpt
Mechanisms associated with reactivation of hepatitis B virus (HBV) in patients with occult HBV infection (OBI) remain unclear. In some cases immunosuppression is an enhancer of viral replication. However, not all patients with OBI who undergo immunosuppression experience reactivation. This study explores the role of viral heterogeneity as a determinant of occult HBV reactivation. HBV genotype, mutation patterns...
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