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Article

Endothelial cell protein C receptor gene 6936A/G and 4678G/C polymorphisms as risk factors for deep venous thrombosis.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 2016

Zoheir Naguib, Eldanasouri Nabiel, Abdel-Aal Asmaa A, Hosny Karim Adel, Abdel-Ghany Wafaa M

Abstract excerpt

Endothelial cell protein C receptor (EPCR) enhances the generation of activated protein C by the thrombin-thrombomodulin complex. A soluble form of EPCR (sEPCR) is present in plasma. Two polymorphisms in the EPCR gene (6936A/G and 4678G/C) have been reported to influence the risk of venous thromboembolism. We aimed to investigate the relation between EPCR gene polymorphisms (6936A/G and 4678C/G) and deep venous...

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Identifiers

PMID: 26340463
DOI: 10.1097/MBC.0000000000000402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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