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Article

Relationship between endothelial cell protein C receptor gene 6936A/G polymorphisms and deep venous thrombosis.

Chinese medical journal - 1 Jan 2011

Chen Xu-Dong, Tian Lu, Li Ming, Jin Wei, Zhang Hong-Kun, Zheng Cheng-Fei

Abstract excerpt

BACKGROUND: Deep venous thrombosis (DVT) can result in pulmonary embolism, a fatal complication that is due to the dislodgement and movement of a blood clot (thrombus) from a limb into the lungs. Genetic risk factors related to DVT development include mutations in coagulation proteins, especially the endothelial protein C receptor (EPCR), a component of the anticoagulation protein C (PC) pathway. The objective of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21362311

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