Article
Dynamic Transmission of Protein Allostery without Structural Change: Spatial Pathways or Global Modes?
Biophysical journal - 15 Sept 2015
McLeish Tom C B, Cann Martin J, Rodgers Thomas L
Abstract excerpt
We examine the contrast between mechanisms for allosteric signaling that involve structural change, and those that do not, from the perspective of allosteric pathways. In particular we treat in detail the case of fluctuation-allostery by which amplitude modulation of the thermal fluctuations of the elastic normal modes conveys the allosteric signal, and address the question of what an allosteric pathway means in...
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