Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline variation of TNFAIP3 in primary Sjögren's syndrome-associated lymphoma.

Annals of the rheumatic diseases - 1 Apr 2016

Nocturne Gaetane, Tarn Jessica, Boudaoud Saida, Locke James, Miceli-Richard Corinne, Hachulla Eric, Dubost Jean-Jacques, Bowman Simon, Gottenberg Jacques-Eric, Criswell Lindsey A, Lessard Christopher J, Sivils Kathy L, Carapito Raphael, Bahram Siamak, Seror Raphaèle, Ng Wan-Fai, Mariette Xavier

Abstract excerpt

BACKGROUND AND OBJECTIVE: A germline and coding polymorphism (rs2230926) of TNFAIP3 (A20), a central gatekeeper of nuclear factor-kappa B (NF-kB) activation, was recently found associated with primary Sjögren's syndrome (pSS)-associated lymphoma in a French cohort. We aimed to replicate this association. PATIENTS AND METHODS: The rs2230926 polymorphism was genotyped in cases and controls of European ancestry from...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share this publication in a Topic to start or enrich a Post.

Share to France
Share to Hodgkin Disease
Share to Lymphoma
Share to Lymphoma, B-Cell
Share to Mycosis Fungoides
Share to Sjogren's Syndrome
Share to Tumor Necrosis Factor alpha-Induced Protein 3
Share to United Kingdom

Source

Identifiers

PMID: 26338037
DOI: 10.1136/annrheumdis-2015-207731

Genes

TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline variation of TNFAIP3 in primary Sjögren's syndrome-associated lymphoma.PMID 26338037Read ↗

Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome.Semantic proximity Read ↗

Haploinsufficiency of TNFAIP3 (A20) by germline mutation is involved in autoimmune lymphoproliferative syndrome.Semantic proximity Read ↗

Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases.Semantic proximity Read ↗

Identification of a Novel Mutation in TNFAIP3 in a Family With Poly-Autoimmunity.Semantic proximity Read ↗

Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia.Semantic proximity Read ↗

B-cell activating factor genetic variants in lymphomagenesis associated with primary Sjogren's syndrome.Semantic proximity Read ↗

Associations between TNFSF13B polymorphisms and primary Sjögren's syndrome susceptibility in primary Sjögren's syndrome patients: A meta-analysis.Semantic proximity Read ↗

Haploinsufficiency of A20 caused by a novel nonsense variant or entire deletion of TNFAIP3 is clinically distinct from Behçet’s diseaseSemantic proximity Read ↗

Contribution of Genetic Factors to Sjögren's Syndrome and Sjögren's Syndrome Related Lymphomagenesis.Semantic proximity Read ↗

Association studies of TNFSF4, TNFAIP3 and FAM167A-BLK polymorphisms with primary Sjogren's syndrome in Han Chinese.Semantic proximity Read ↗

Association of the TNFAIP3 rs5029939 variant with systemic sclerosis in the European Caucasian population.Semantic proximity Read ↗

Genetic Mutations Associated With TNFAIP3 (A20) Haploinsufficiency and Their Impact on Inflammatory Diseases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.