Article
Analysis of Epidermal Growth Factor Receptor Mutations in Serum Among Japanese Patients Treated With First-Line Erlotinib for Advanced Non-Small-Cell Lung Cancer.
Clinical lung cancer - 1 Jan 2016
Nishio Makoto, Goto Koichi, Chikamori Kenichi, Hida Toyoaki, Katakami Nobuyuki, Maemondo Makoto, Ohishi Norihisa, Tamura Tomohide
Abstract excerpt
BACKGROUND: Obtaining tumor samples for epidermal growth factor receptor (EGFR) mutation analysis during treatment can be difficult; therefore, serum samples may be a convenient alternative. We analyzed serum EGFR mutations in the Japanese phase 2 JO22903 study in chemotherapy-naive non-small-cell lung cancer patients with tumor EGFR mutations. MATERIALS AND METHODS: Serum samples were analyzed by Scorpion-ARMS...
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