Article
SV40 transcription terminators stabilize the activity of regulatory elements in Drosophila melanogaster.
Doklady. Biochemistry and biophysics - 1 Jan 2015
Chetverina D A, Elizar'ev P V, Georgiev P G, Erokhin M M
Abstract excerpt
To ensure stable operation of transgenic systems and maintain reporter gene expression at a certain level, it is necessary to search for the conditions that protect the activity of regulatory elements. In this study, we have shown that the SV40 transcription terminators flanking the transgene protect enhancers and silencers of Drosophila and ensure their efficient functioning.
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