Article
Genetic polymorphism c.1562C>T of the MMP-9 is associated with macroangiopathy in type 2 diabetes mellitus.
Biochemical and biophysical research communications - 1 Jan 2010
Wang Ying, Su Ying, Xu Ying, Pan Shang-Ha, Liu Guo-Dong
Abstract excerpt
OBJECTIVE: To determine whether the matrix metalloproteinase-9 (MMP-9) c.1562C>T polymorphism has an effect on the plasma MMP-9 levels and the macroangiopathic complications in type 2 diabetes mellitus (T2DM). METHODS: The genotypes and allelic frequencies of the MMP-9 c.1562C>T were examined with polymerase chain reaction and restriction fragment length polymorphism in 320 patients with T2DM and 160 unrelated...
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