Article
Expression of RAP1B is associated with poor prognosis and promotes an aggressive phenotype in gastric cancer.
Oncology reports - 1 Nov 2015
Yang Ya, Li Min, Yan Yan, Zhang Jia, Sun Kai, Qu Jing-Kun, Wang Jian-Sheng, Duan Xiao-Yi
Abstract excerpt
Metastasis is the major cause of death among gastric cancer (GC) patients, and altered expression of Ras-related protein RAP1B is associated with cancer development. The present study assessed RAP1B expression ex vivo and the effect of hypoxia‑induced RAP1B overexpression on the promotion of the...
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