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Article

Pedigree-based Analysis of Inherited and Noninherited Risk Factors of Congenital Heart Defects.

Early human development - 1 Dec 2015

Yuan Yuan, Chen Weicheng, Ma Xiaojing, Wang Huijun, Yan Weili, Huang Guoying

Abstract excerpt

BACKGROUND: Although congenital heart defect (CHD) pedigrees are rare, they are generally taken as evidence of the existence of a genetic etiologic mechanism or environmental factors common to family members, or a combination of both. Therefore, the analysis of CHD pedigrees is important for bridging the gap in our knowledge of its etiology. AIMS: To assess the prevalence of CHD and evaluate the nongenetic...

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PMID: 26324253
DOI: 10.1016/j.earlhumdev.2015.08.001

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