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Article

Influence of genes and the environment in familial congenital heart defects

6 Dec 2013

Abstract excerpt

The present study aimed to investigate genetic and environmental factors involved in the pathogenesis of congenital heart disease (CHD). A total of 61 familial pedigrees with CHD were analyzed, and 134 patients out of 761 family members had a diagnosis of CHD confirmed. The present study revealed that the prevalence of CHD in first‑degree relatives (55/249, 22.0%) was significantly higher than that in...

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PMID: 24337398
DOI: 10.3892/mmr.2013.1847

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