Article
Tumorigenicity analysis of heterogeneous dental stem cells and its self-modification for chromosome instability.
Cell cycle (Georgetown, Tex.) - 1 Jan 2015
Meng Zhaosong, Chen Guoqing, Chen Jinlong, Yang Bo, Yu Mei, Feng Lian, Jiang Zongting, Guo Weihua, Tian Weidong
Abstract excerpt
Heterogeneity demonstrates that stem cells are constituted by several sub-clones in various differentiation states. The heterogeneous state is maintained by cross-talk among sub-clones, thereby ensuring stem cell adaption. In this study, we investigated the roles of heterogeneity on genetic stability. Three sub-clones (DF2, DF8 and DF18) were isolated from heterogeneous dental stem cells (DSCs), and were proved...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
