Article
Thyroid transcription factor-2 gene expression in benign and malignant thyroid lesions.
Thyroid : official journal of the American Thyroid Association - 1 Nov 2001
Sequeira M J, Morgan J M, Fuhrer D, Wheeler M H, Jasani B, Ludgate M
Abstract excerpt
Thyroid transcription factor-2 (TTF-2) is a recently cloned thyroid-specific gene and is central to the development and differentiation of the thyroid follicular cell. Information regarding transcript levels in normal and diseased adult human thyroids is lacking. We have investigated TTF-2 gene expression in various thyroid pathologies and assessed its potential in preoperative diagnosis of thyroid nodular...
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