Article
Sphere-derived tumor cells exhibit impaired metastasis by a host-mediated quiescent phenotype.
Oncotarget - 29 Sept 2015
Bleau Anne-Marie, Zandueta Carolina, Redrado Miriam, Martínez-Canarias Susana, Larzábal Leyre, Montuenga Luis M, Calvo Alfonso, Lecanda Fernando
Abstract excerpt
The spread of lung cancer cells to distant sites represents a common event associated with poor prognosis. A fraction of tumor cells named cancer stem cells (CSCs) have the ability to overcome therapeutic stress and remain quiescent. However, whether these CSCs have also the capacity to initiate...
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