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Article

Metastatic potential of tumor-initiating cells in solid tumors

28 Nov 2010

Abstract excerpt

The lethality of cancer is mainly caused by its properties of metastasis, drug resistance, and subsequent recurrence. Understanding the mechanisms governing these properties and developing novel strategies to overcome them will greatly improve the survival of cancer patients. Recent findings suggest that tumors are comprised of heterogeneous cell populations, and only a small fraction of these are tumorigenic...

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PMID: 21196274
DOI: 10.2741/3831

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