Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms associated with the inflammatory response in bacterial meningitis.

BMC medical genetics - 28 Aug 2015

Fontes Fabrícia Lima, de Araújo Luíza Ferreira, Coutinho Leonam Gomes, Leib Stephen L, Agnez-Lima Lucymara Fassarella

Abstract excerpt

BACKGROUND: Bacterial meningitis (BM) is an infectious disease that results in high mortality and morbidity. Despite efficacious antibiotic therapy, neurological sequelae are often observed in patients after disease. Currently, the main challenge in BM treatment is to develop adjuvant therapies that reduce the occurrence of sequelae. In recent papers published by our group, we described the associations between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Inflammation
Share to Interleukin-8

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Meningitis, Bacterial

Share to Odds Ratio

Share to Polymorphism, Restriction Fragment Length

Share to Statistics, Nonparametric

Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 26316174
DOI: 10.1186/s12881-015-0218-6
PMCID: PMC4593216

Genes

TNF
AADAT
APEX1
OGG1
PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms associated with the inflammatory response in bacterial meningitis.PMID 26316174Read ↗

SNPs in DNA repair genes associated to meningitis and host immune response.Semantic proximity Read ↗

Comparison of cytokine gene polymorphisms among Greek patients with invasive meningococcal disease or viral meningitis.Semantic proximity Read ↗

Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis.Semantic proximity Read ↗

Single nucleotide polymorphisms in pathogen recognition receptor genes are associated with susceptibility to meningococcal meningitis in a pediatric cohort.Semantic proximity Read ↗

Genes and their single nucleotide polymorphism involved in innate immune response in central nervous system in bacterial meningitis: review of literature data.Semantic proximity Read ↗

How many single-nucleotide polymorphisms (SNPs) must be tested in order to prove susceptibility to bacterial meningitis in children? Analysis of 11 SNPs in seven genes involved in the immune response and their effect on the susceptibility to bacterial meningitis in children.Semantic proximity Read ↗

TLR9 Rs352140 polymorphism contributes to a decreased risk of bacterial meningitis: evidence from a meta-analysis.Semantic proximity Read ↗

Single nucleotide polymorphisms in TLR9 are highly associated with susceptibility to bacterial meningitis in children.Semantic proximity Read ↗

Genetic variations of toll-like receptors: Impact on susceptibility, severity and prognosis of bacterial meningitis.Semantic proximity Read ↗

Genetic variation in inflammasome genes is associated with outcome in bacterial meningitis.Semantic proximity Read ↗

CARD8 polymorphisms among bacterial meningitis patients in North-West EthiopiaSemantic proximity Read ↗

Gene polymorphisms of TLR10: effects on bacterial meningitis outcomes in Angolan children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.