Liver Transplantation for Hereditary Transthyretin Amyloidosis: After 20 Years Still the Best Therapeutic Alternative?

doi:10.1097/TP.0000000000000574

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Liver Transplantation for Hereditary Transthyretin Amyloidosis: After 20 Years Still the Best Therapeutic Alternative?

Transplantation - 1 Sept 2015

Ericzon Bo-Göran, Wilczek Henryk E, Larsson Marie, Wijayatunga Priyantha, Stangou Arie, Pena João Rodrigues, Furtado Emanuel, Barroso Eduardo, Daniel Jorge, Samuel Didier, Adam Rene, Karam Vincent, Poterucha John, Lewis David, Ferraz-Neto Ben-Hur, Cruz Márcia Waddington, Munar-Ques Miguel, Fabregat Juan, Ikeda Shu-Ichi, Ando Yukio, Heaton Nigel, Otto Gerd, Suhr Ole

Abstract excerpt

BACKGROUND: Until recently, liver transplantation (Ltx) was the only available treatment for hereditary transthyretin (TTR) amyloidosis; today, however, several pharmacotherapies are tested. Herein, we present survival data from the largest available database on transplanted hereditary TTR patients to serve as a base for comparison. METHODS: Liver transplantation was evaluated in a 20-year retrospective analysis...

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PMID: 26308415
DOI: 10.1097/TP.0000000000000574

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