Article
Liver transplantation in transthyretin amyloidosis: Characteristics and management related to kidney disease.
Transplantation reviews (Orlando, Fla.) - 1 Apr 2017
Rocha Ana, Lobato Luísa
Abstract excerpt
Orthotopic liver transplantation (LT) was implemented as the inaugural disease-modifying therapy for hereditary transthyretin (ATTR) amyloidosis, a systemic amyloidosis mainly affecting the peripheral nervous system and heart. The first approach to pharmacologic therapy was focused on the stabilization of the TTR tetramer; following that new advent LT was assumed as the second step of treatment, for those...
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