Article
An assessment of sex bias in neurodevelopmental disorders.
Genome medicine - 27 Aug 2015
Polyak Andrew, Rosenfeld Jill A, Girirajan Santhosh
Abstract excerpt
BACKGROUND: Neurodevelopmental disorders such as autism and intellectual disability have a sex bias skewed towards boys; however, systematic assessment of this bias is complicated by the presence of significant genetic and phenotypic heterogeneity of these disorders. METHODS: To assess the extent and characteristics of sex bias, we analyzed the frequency of comorbid features, the magnitude of genetic load, and...
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