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Article

eIF4E/Fmr1 double mutant mice display cognitive impairment in addition to ASD-like behaviors.

Neurobiology of disease - 1 Nov 2015

Huynh Thu N, Shah Manan, Koo So Yeon, Faraud Kirsten S, Santini Emanuela, Klann Eric

Abstract excerpt

Autism spectrum disorder (ASD) is a group of heritable disorders with complex and unclear etiology. Classic ASD symptoms include social interaction and communication deficits as well as restricted, repetitive behaviors. In addition, ASD is often comorbid with intellectual disability. Fragile X syndrome (FXS) is the leading genetic cause of ASD, and is the most commonly inherited form of intellectual disability....

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Source

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Identifiers

PMID: 26306459
DOI: 10.1016/j.nbd.2015.08.016
PMCID: PMC4674395

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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