Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.

doi:10.1001/jama.2015.9643

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Article

Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia.

JAMA - 25 Aug 2015

Klco Jeffery M, Miller Christopher A, Griffith Malachi, Petti Allegra, Spencer David H, Ketkar-Kulkarni Shamika, Wartman Lukas D, Christopher Matthew, Lamprecht Tamara L, Helton Nicole M, Duncavage Eric J, Payton Jacqueline E, Baty Jack, Heath Sharon E, Griffith Obi L, Shen Dong, Hundal Jasreet, Chang Gue Su, Fulton Robert, O'Laughlin Michelle, Fronick Catrina, Magrini Vincent, Demeter Ryan T, Larson David E, Kulkarni Shashikant, Ozenberger Bradley A, Welch John S, Walter Matthew J, Graubert Timothy A, Westervelt Peter, Radich Jerald P, Link Daniel C, Mardis Elaine R, DiPersio John F, Wilson Richard K, Ley Timothy J

Abstract excerpt

IMPORTANCE: Tests that predict outcomes for patients with acute myeloid leukemia (AML) are imprecise, especially for those with intermediate risk AML. OBJECTIVES: To determine whether genomic approaches can provide novel prognostic information for adult patients with de novo AML. DESIGN, SETTING, AND PARTICIPANTS: Whole-genome or exome sequencing was performed on samples obtained at disease presentation from 71...

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Identifiers

PMID: 26305651
DOI: 10.1001/jama.2015.9643
PMCID: PMC4621257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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