Article
Comparison of significant single nucleotide polymorphisms selections in GWAS for complex traits.
Journal of applied genetics - 1 May 2016
Frąszczak M, Szyda J
Abstract excerpt
The goal of this study was to compare significant SNP selection approaches in the context of complex traits based on SNP estimates obtained by models: a model fitting a single SNP (M1), a model fitting a single SNP and a random polygenic effect (M2), the nonparametric CAR score (M3), a SNP-BLUP model with random effects of all SNPs fitted simultaneously (M4). There were 46,267 SNPs tested in a population of 2601...
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