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The Neuronal Pentraxin-2 Pathway Is an Unrecognized Target in Human Neuroblastoma, Which Also Offers Prognostic Value in Patients

20 Aug 2015

Abstract excerpt

Neuronal pentraxins (NPTX) and their corresponding receptors (NPTXR) have been studied as synapse-associated proteins in the nervous system, but their role in cancer is largely unknown. By applying a multidisciplinary, high-throughput proteomic approach, we have recently identified a peptide ligand motif for targeted drug delivery to neuroblastoma. Here, we report the sequence similarity between this peptide and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26294210
DOI: 10.1158/0008-5472.can-15-0649

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