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Neuropilins Controlling Cancer Therapy Responsiveness

25 Apr 2019

Abstract excerpt

Neuropilins (NRPs) are cell surface glycoproteins, acting as co-receptors for secreted Semaphorins (SEMAs) and for members of the vascular endothelial growth factor (VEGF) family; they have been initially implicated in axon guidance and angiogenesis regulation, and more recently in cancer progression. In addition, NRPs have been shown to control many other fundamental signaling pathways, especially mediated by...

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PMID: 31027288
DOI: 10.3390/ijms20082049

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