Article
The role of miRNAs in stress-responsive hepatic stellate cells during liver fibrosis
28 Jul 2015
Abstract excerpt
The progression of liver fibrosis and cirrhosis is associated with the persistence of an injury causing agent, leading to changes in the extracellular environment and a disruption of the cellular homeostasis of liver resident cells. Recruitment of inflammatory cells, apoptosis of hepatocytes, and changes in liver microvasculature are some examples of changing cellular environment that lead to the induction of...
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