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microRNAs: Fad or future of liver disease

1 Jan 2011

Abstract excerpt

microRNAs (miRs) are small non-coding RNAs that regulate both mRNA and protein expression of target genes, which results in alterations in mRNA stability or translation inhibition. miRs influence at least one third of all human transcripts and are known regulators of various important cellular growth and differentiation factors. miRs have recently emerged as key regulatory molecules in chronic liver disease. This...

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PMID: 21633658
DOI: 10.3748/wjg.v17.i20.2536

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