Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinicopathological Significance and Potential Drug Target of CDKN2A/p16 in Endometrial Carcinoma.

Scientific reports - 18 Aug 2015

Su Li, Wang Hanwei, Miao Jingwei, Liang Ying

Abstract excerpt

Previous studies demonstrated that the loss of function of the CDKN2A/p16/INK4A gene is mainly caused by the hypermethylation of CDKN2A, however, whether or not it is associated with the incidence and clinicopathological characteristics of endometrial carcinoma (EC) remains unclear. In this study, we conducted a meta-analysis aiming to comprehensively assess the role of CDKN2A hypermethylation in the pathogenesis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endometrial Neoplasms

Share to Genetic Markers

Share to Neoplasm Proteins

Share to Polymorphism, Single Nucleotide

Share to Prevalence

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 26283007
DOI: 10.1038/srep13238
PMCID: PMC4642515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathological Significance and Potential Drug Target of CDKN2A/p16 in Endometrial Carcinoma.PMID 26283007Read ↗

Unveiling DNA methylation: early diagnosis, risk assessment, and therapy for endometrial cancerSemantic proximity Read ↗

Identification of DNA methylation associated gene signatures in endometrial cancer via integrated analysis of DNA methylation and gene expression systematicallySemantic proximity Read ↗

CDK4/RB/E2Fs axis as potential therapeutic target of endometrial cancer.Semantic proximity Read ↗

Epigenetic mechanisms in endometrial cancer.Semantic proximity Read ↗

Bioinformatics approaches to multi-omics analysis of the potential of CDKN2A as a biomarker and therapeutic target for uterine corpus endometrial carcinomaSemantic proximity Read ↗

KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1Semantic proximity Read ↗

Association between P16INK4a Promoter Methylation and Ovarian Cancer: A Meta-Analysis of 12 Published Studies.Semantic proximity Read ↗

Association of genetic polymorphisms in AURKA, BRCA1, CCNE1 and CDK2 with the risk of endometrial carcinoma and clinicopathological parameters among Chinese Han women.Semantic proximity Read ↗

DNA methylation as mechanism of apoptotic resistance development in endometrial cancer patients.Semantic proximity Read ↗

Evaluation value of miR-26a/b-5p on survival prognosis of endometrial carcinoma and identification of its relationship with epigenetic modifier gene EZH2Semantic proximity Read ↗

Systematic Analysis of the Clinical Relevance of Cell Division Cycle Associated Family in Endometrial CarcinomaSemantic proximity Read ↗

Relationship Between Murine Double Minute 2 (MDM2) T309G Polymorphism and Endometrial Cancer Risk: A Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.