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Article

DNA methylation as mechanism of apoptotic resistance development in endometrial cancer patients.

General physiology and biophysics - 1 Dec 2017

Fialkova Veronika, Vidomanova Eva, Balharek Tomas, Marcinek Juraj, Kudela Erik, Hanysova Sandra, Visnovsky Jozef, Dobrota Dusan, Hatok Jozef

Abstract excerpt

DNA methylation is a significant epigenetic modification which plays a key role in regulation of gene expression and influences functional changes in endometrial tissue. Aberrant DNA methylation changes result in deregulation of important apoptotic proteins during endometrial carcinogenesis and apoptosis resistance development. Evading apoptosis is still a major problem in the successful treatment of endometrial...

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Identifiers

PMID: 29372685
DOI: 10.4149/gpb_2017032

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BIK
CIDEB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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