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Article

A Novel Statistic for Global Association Testing Based on Penalized Regression.

Genetic epidemiology - 1 Sept 2015

Austin Erin, Shen Xiaotong, Pan Wei

Abstract excerpt

Natural genetic structures like genes may contain multiple variants that work as a group to determine a biologic outcome. The effect of rare variants, mutations occurring in less than 5% of samples, is hypothesized to be explained best as groups collectively associated with a biologic function. T...

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PMID: 26282998
DOI: 10.1002/gepi.21915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26282998-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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