Article
Functional connectivity measures as schizophrenia intermediate phenotypes: advances, limitations, and future directions.
Current opinion in neurobiology - 1 Feb 2016
Cao Hengyi, Dixson Luanna, Meyer-Lindenberg Andreas, Tost Heike
Abstract excerpt
The search for quantifiable biological mediators of genetic risk or 'intermediate phenotypes' is an essential strategy in psychiatric neuroscience and a useful tool for exploring the complex relationships between genes, neural circuits and behaviors. In recent years, the examination of connectivity-based intermediate phenotypes has gained increasing popularity in the study of schizophrenia, a brain disorder that...
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