PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers: clinicopathologic, immunohistochemical, and molecular characteristics suggesting classification as a distinct entity.

doi:10.1097/PAS.0000000000000502

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers: clinicopathologic, immunohistochemical, and molecular characteristics suggesting classification as a distinct entity.

The American journal of surgical pathology - 1 Sept 2015

Rao Qiu, Shen Qin, Xia Qiu-yuan, Wang Zi-yu, Liu Biao, Shi Shan-shan, Shi Qun-li, Yin Hong-lin, Wu Bo, Ye Sheng-bing, Li Li, Chen Jie-Yu, Pan Min-hong, Li Qing, Li Rui, Wang Xuan, Zhang Ru-song, Yu Bo, Ma Heng-hui, Lu Zhen-feng, Zhou Xiao-jun

Abstract excerpt

An increasing number of TFE3 rearrangement-associated tumors, such as TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas), melanotic Xp11 translocation renal cancers, and melanotic Xp11 neoplasms, have recently been reported. We examined 12 such cases, including 5 TFE3 rearrangement-associated PEComas located in the pancreas, cervix, or pelvis and 7 melanotic Xp11 translocation renal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Leucine Zipper Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, X

Share to Gene Fusion

Share to Gene Rearrangement

Share to Kidney Neoplasms

Share to Mitosis

Share to Molecular Diagnostic Techniques

Share to Translocation, Genetic

Source

Open in PubMed

Identifiers

PMID: 26274027
DOI: 10.1097/PAS.0000000000000502

Genes

PAX8
SFPQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers: clinicopathologic, immunohistochemical, and molecular characteristics suggesting classification as a distinct entity.PMID 26274027Read ↗

SFPQ/PSF-TFE3 renal cell carcinoma: a clinicopathologic study emphasizing extended morphology and reviewing the differences between SFPQ-TFE3 RCC and the corresponding mesenchymal neoplasm despite an identical gene fusion.Semantic proximity Read ↗

TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation CancersSemantic proximity Read ↗

Xp11 Translocation Renal Cell Carcinomas (RCCs) With RBM10-TFE3 Gene Fusion Demonstrating Melanotic Features and Overlapping Morphology With t(6;11) RCC: Interest and Diagnostic Pitfall in Detecting a Paracentric Inversion of TFE3.Semantic proximity Read ↗

Malignant Perivascular Epithelioid Cell Neoplasm (PEComa) of the Urinary Bladder With TFE3 Gene RearrangementSemantic proximity Read ↗

Melanotic PEComa of the Sinonasal Mucosa With NONO-TFE3 FusionSemantic proximity Read ↗

TFE3-rearranged nonmelanotic renal PEComa: a case series expanding their phenotypic and fusion landscape.Semantic proximity Read ↗

A Distinctive Subset of PEComas Harbors TFE3 Gene FusionsSemantic proximity Read ↗

Melanotic Xp11 translocation renal cancer: report of a case with a unique intratumoral sarcoid-like reaction.Semantic proximity Read ↗

PEComa with ASPSCR1::TFE3 fusion: expanding the molecular genetic spectrum of TFE3‐rearranged PEComa with an emphasis on overlap with alveolar soft part sarcomaSemantic proximity Read ↗

PEComa-like Neoplasms Characterized by ASPSCR1-TFE3 FusionSemantic proximity Read ↗

Melanotic Translocation Renal Cell Carcinoma With a Novel ARID1B-TFE3 Gene Fusion.Semantic proximity Read ↗

Melanotic Xp11 translocation renal cancer: a report of a distinctive case and a review of the literature.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.