Xp11 Translocation Renal Cell Carcinomas (RCCs) With RBM10-TFE3 Gene Fusion Demonstrating Melanotic Features and Overlapping Morphology With t(6;11) RCC: Interest and Diagnostic Pitfall in Detecting a Paracentric Inversion of TFE3.

doi:10.1097/PAS.0000000000000837

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Xp11 Translocation Renal Cell Carcinomas (RCCs) With RBM10-TFE3 Gene Fusion Demonstrating Melanotic Features and Overlapping Morphology With t(6;11) RCC: Interest and Diagnostic Pitfall in Detecting a Paracentric Inversion of TFE3.

The American journal of surgical pathology - 1 May 2017

Xia Qiu-Yuan, Wang Xiao-Tong, Zhan Xue-Mei, Tan Xiao, Chen Hao, Liu Yi, Shi Shan-Shan, Wang Xuan, Wei Xue, Ye Sheng-Bing, Li Rui, Ma Heng-Hui, Lu Zhen-Feng, Zhou Xiao-Jun, Rao Qiu

Abstract excerpt

Xp11 translocation renal cell carcinomas (RCC) are characterized by several different translocations involving the TFE3 gene. Tumors with different specific gene fusions may have different clinicopathologic manifestations. Only 3 RBM10-TFE3 RCCs have been reported to date. Here, we added 4 cases of this rare type of tumors with clinicopathologic, immunohistochemical, molecular, and ultrastructural analyses. Most...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Leucine Zipper Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Renal Cell

Share to Cathepsin K

Share to Chromosome Inversion

Share to Chromosomes, Human, Pair 11

Share to Chromosomes, Human, Pair 6

Share to Gene Fusion

Share to Melanins

Source

Open in PubMed

Identifiers

PMID: 28288037
DOI: 10.1097/PAS.0000000000000837

Genes

RBM10
PAX8
TFEB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Xp11 Translocation Renal Cell Carcinomas (RCCs) With RBM10-TFE3 Gene Fusion Demonstrating Melanotic Features and Overlapping Morphology With t(6;11) RCC: Interest and Diagnostic Pitfall in Detecting a Paracentric Inversion of TFE3.PMID 28288037Read ↗

SFPQ/PSF-TFE3 renal cell carcinoma: a clinicopathologic study emphasizing extended morphology and reviewing the differences between SFPQ-TFE3 RCC and the corresponding mesenchymal neoplasm despite an identical gene fusion.Semantic proximity Read ↗

RBM10‐TFE3 fusions: A FISH‐concealed anomaly in adult renal cell carcinomas displaying a variety of morphological and genomic features: Comprehensive study of six novel casesSemantic proximity Read ↗

MiT family translocation renal cell carcinoma in an elderly maleSemantic proximity Read ↗

Melanotic Translocation Renal Cell Carcinoma With a Novel ARID1B-TFE3 Gene Fusion.Semantic proximity Read ↗

PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers: clinicopathologic, immunohistochemical, and molecular characteristics suggesting classification as a distinct entity.Semantic proximity Read ↗

RBM10–TFE3 renal cell carcinoma characterised by paracentric inversion with consistent closely split signals in break‐apart fluorescence in‐situ hybridisation: study of 10 cases and a literature reviewSemantic proximity Read ↗

MiT Family Translocation-Associated Renal Cell Carcinoma: A Contemporary Update With Emphasis on Morphologic, Immunophenotypic, and Molecular MimicsSemantic proximity Read ↗

Translocation Renal Cell Carcinoma: An Update on Clinicopathological and Molecular FeaturesSemantic proximity Read ↗

Xp11 Translocation Renal Cell Carcinoma in Adults: Expanded Clinical, Pathologic, and Genetic SpectrumSemantic proximity Read ↗

Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysisSemantic proximity Read ↗

Identification by FFPE RNA‐Seq of a new recurrent inversion leading to RBM10‐TFE3 fusion in renal cell carcinoma with subtle TFE3 break‐apart FISH patternSemantic proximity Read ↗

Xp11.2 translocation renal cell carcinoma with NONO-TFE3 gene fusion: morphology, prognosis, and potential pitfall in detecting TFE3 gene rearrangementSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.