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Article

Redox Regulation in Cancer Stem Cells

1 Jan 2015

Abstract excerpt

Reactive oxygen species (ROS) and ROS-dependent (redox regulation) signaling pathways and transcriptional activities are thought to be critical in stem cell self-renewal and differentiation during growth and organogenesis. Aberrant ROS burst and dysregulation of those ROS-dependent cellular processes are strongly associated with human diseases including many cancers. ROS levels are elevated in cancer cells...

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PMID: 26273424
DOI: 10.1155/2015/750798

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