Article
Assessment of the Impact of Potential Tetracycline Exposure on the Phenotype of Aedes aegypti OX513A: Implications for Field Use.
PLoS neglected tropical diseases - 1 Aug 2015
Curtis Zoe, Matzen Kelly, Neira Oviedo Marco, Nimmo Derric, Gray Pamela, Winskill Peter, Locatelli Marco A F, Jardim Wilson F, Warner Simon, Alphey Luke, Beech Camilla
Abstract excerpt
BACKGROUND: Aedes aegypti is the primary vector of dengue fever, a viral disease which has an estimated incidence of 390 million infections annually. Conventional vector control methods have been unable to curb the transmission of the disease. We have previously reported a novel method of vector control using a tetracycline repressible self-limiting strain of Ae. aegypti OX513A which has achieved >90% suppression...
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