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Fitness of Transgenic Mosquito Aedes aegypti Males Carrying a Dominant Lethal Genetic System

14 May 2013

Abstract excerpt

OX513A is a transgenic strain of Aedes aegypti engineered to carry a dominant, non-sex-specific, late-acting lethal genetic system that is repressed in the presence of tetracycline. It was designed for use in a sterile-insect (SIT) pest control system called RIDL® (Release of Insects carrying a Dominant Lethal gene) by which transgenic males are released in the field to mate with wild females; in the absence of...

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PMID: 23690948
DOI: 10.1371/journal.pone.0062711

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