Article
[Genetic polymorphisms in X-ray repair cross-complementing gene 1 and susceptibility to papillary thyroid carcinoma].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Aug 2004
Zhu Qian-Xi, Bian Jian-Chao, Shen Qiang, Jiang Feng, Tang Hong-Wei, Zhang Hong-Wei, Wu Yi
Abstract excerpt
OBJECTIVE: To study the association of polymorphisms in the X-ray repair cross-complementing gene 1 (XRCC1) and papillary thyroid carcinoma (PTC). METHODS: A hospital based, matched case-control study was carried out. The polymorphisms in XRCC1 for 105 pairs of cases with PTC and controls were identified by PCR-RFLP. RESULTS: The frequencies of Arg/Arg, Arg/Trp and Trp/Trp genotypes at XRCC1 Arg194Trp site were...
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